
Many theories have been proposed - viral infection, environmental poisons, metabolic disturbance and genetic defects. Although the answer has not yet been found, research funded by Motor Neurone Disease Associations is expanding rapidly world-wide.
See Research.
Usually it is not difficult for a Neurologist to diagnose MND on the basis of the history and signs. Early signs may cause some initial difficulty. There is no specific laboratory test. Sometimes special tests, possibly including a brain and spine MRI, are necessary to exclude other diseases. Usually, electrical tests on muscles and nerves are performed and a lumbar puncture and muscle biopsy may be done.
Approximately one in 50,000 will develop MND in any one year, with 250 patients in Ireland at any one time. Most patients are adults.
